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Type 2 Diabetes and TZDs (Thiazolidinediones)

When you have type 2 diabetes, your blood glucose (sugar) levels are higher than normal. Blood glucose comes mainly from the food you eat, and some is produced by your liver. Your body uses glucose for energy with the help of insulin, a hormone made by your pancreas. You can develop type 2 diabetes when your body

• doesn’t make enough insulin
• doesn’t use insulin the way it should, a condition called insulin resistance

Most people with type 2 diabetes have both problems. Middle-aged and older people are more likely to develop type 2 diabetes. So are people who are overweight (especially around the waist) and physically inactive.

High blood glucose levels over time can lead to serious health problems, such as blindness, nerve damage, kidney disease, heart attacks, and strokes. But keeping blood glucose, blood pressure, and cholesterol levels on target with meal planning, exercise, and medicines (if needed) can prevent or delay these problems.

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The Hormone Foundation

Dr. Lysette Iglesias M.D.

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